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Donner Doudoune Pjs Pas Cher UGO Super Lightweight Spring 2014 Homme Gilete Royale

Donner Doudoune Pjs Pas Cher UGO Super Lightweight Spring 2014 Homme Gilete Royale

In vitro Belstaff Pas Cher neuronal damage has traditionally been evaluated by biochemical or anatomical but not by electrophysiological techniques. In the present study, we Belstaff Sac 554 combined two newly developed technologies, an 8×8 multi-electrode array (MED-64) and cultured hippocampal slices, to demonstrate the potential use of Belstaff France electrophysiological measures as index of neuronal damage. We first demonstrated the stability of electrophysiological recordings over prolonged periods of time (up to 14 days) in field CA1 of cultured hippocampal slices following electrical stimulation of the Schaffer collateral pathway. We then assessed the neurotoxic properties of NMDA and AMPA and determined that the time-course, potency, and efficacy of these two neurotoxins were similar to those assessed by other experimental approaches. We also compared the efficacy and potency of two non-competitive NMDA receptor antagonists to protect against NMDA-mediated neurotoxicity. Again, the results matched well with the results obtained from traditional techniques. Thus, this new technology might provide a new and powerful method to study the chronic effects of drugs or other experimental manipulations in an in vitro preparation.

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